杜磊

食品科学与工程专业：硕士生导师

生物化工专业：硕士生导师

生物与医药专业（生物工程领域）：硕士生导师

  杜磊，副教授，6165cc金沙总站硕士生导师。2016年毕业于东京海洋大学，获应用生命科学专业博士学位。同年入职深圳大学材料学院从事博士后研究工作，合作导师Florian J. Stadler。2019年入职6165cc金沙总站食品科学与工程系。先后主持国家自然科学基金青年基金、上海市自然科学基金面上项目、微生物技术国家重点实验室（山东大学）开放课题和多项企业横向课题等科研项目。在Food Hydrocoll、Carbohyr Polym、Mol Nutri Food Res、Process Biochem、J Rheology等杂志发表相关研究论文35篇。Polymers杂志客座编辑，Food and Health青年编委。

研究方向：

1. 食品亲水胶体

基于多糖、蛋白等食品亲水胶体的物性表征，研究其在功能性食品、益生菌及功能生物材料等领域的应用。

2. 生物活性肽

基于深度学习的生物活性肽高通量筛选和生物制造，开发功能生物活性肽产品。

3. 益生菌

功能益生菌发掘、高密度发酵及冻干保护剂开发。

主持或参加的国家基金项目：

（1） 国家自然科学基金青年基金项目(31801489)，主持。

（2） 上海市自然科学基金面上项目(21ZR1416200)，主持。

（3） 广东省水产品加工与安全重点实验室开放基金课题(GDPKLAPPS2001)，主持。

（4） 微生物技术国家重点实验室（山东大学）开放课题(62450004042010)，主持。

（5） 国家自然科学基金面上项目(21574086)，项目骨干。

教学：

主讲本科生必修课程《食品工艺学实验》、《专业外语》和《毕业实习》。

代表性论文（*通讯作者）

1. Yuan Zou, Kum-Song. Ro, Chentian Jiang, Deyi Yin, Li Zhao, Daihui Zhang, Lei Du*, Jingli Xie. The anti-hyperuricemic and gut microbiota regulatory effects of a novel purine assimilatory strain, Lactiplantibacillus plantarum X7022, European Journal of Nutrition. 2023, DOI: 10.1007/s00394-023-03291-w.

2. Deyi Yin, Li Zhao, Sijing Deng, Yaqi Xie, Kum-Song Ro, Zeyong Yang, Lei Du*, JingLi Xie*, DongZhi Wei. Lactiplantibacillus plantarum X7022 plays roles on aging mice with memory impairment induced by D-galactose through restoring neuronal damage, relieving inflammation and oxidative stress, Probiotics and Antimicrobial Proteins. 2024, https://doi.org/10.1007/s12602-023-10208-w.

3. Kum-Song Ro, Li Zhao, Yangting Hu, Minli Ge, Lei Du*, Jingli Xie*. Anti-hyperuricemic properties and mechanism of Lactiplantibacillus plantarum X7023. Process Biochemistry. 2024, 136:26-37.

4. Dewei Xie, Yaling Shen, Eezeng Su, Lei Du*, Jingli Xie*, Dongzhi Wei. Anti-hyperuricemic, nephroprotective, and gut microbiota regulative effects of separated hydrolysate of alpha-Lactalbumin on potassium oxonate- and hypoxanthine-induced hyperuricemic mice. Molecular Nutrition & Food Research. 2023, 67(1), 2200162.

5. Lisong Hu, Yitong Xie, Shishuai Gao, Xiaoyu Shi, Chenhuan Lai, Daihui Zhang*, Chuanwei Lu, Yi Liu, Lei Du*, Xuezhi Fang*, Fen. Xu, Chunpeng Wang, Fuxiang Chu. Strain-induced orientation facilitates the fabrication of highly stretchable and tough xylan-based hydrogel for strain sensors. Carbohydrate Polymers. 2023, 312, 120827.

6. Chentian Jiang, Yafan Liu, Yijia Wang, Erzheng Su, Lei Du*, Ya-Jie Tang, Jingli Xie*, Dongzhi Wei. Hypolipidemic effects of the fermented soymilk with a novel Lactiplantibacillus plantarum strain X7021 on mice via modulating lipid metabolism and gut microbiota. International Journal of Food Science and Technology. 2022, 57(7): 4555-4565.

7. Lei Du, Kum-Song Ro, Yiji Zhang, Ya-Jie Tang, Wanbang Li, Jingli Xie*, Dongzhi Wei*. Effects of Lactiplantibacillus plantarum X7021 on physicochemical properties, purines, isoflavones and volatile compounds of fermented soymilk. Process Biochemistry. 2022, 113: 150-157.

8. Dewei Xie, Yunsheng Gao,Lei Du*, Yaling Shen, Jingli Xie, Dongzhi Wei. Effect of flavorzyme-modified soy protein on the functional properties, texture and microstructure of Mozzarella cheese analogue. Journal of Food Processing and Preservation. 2021, 45(11): e15963.

9. Lei Du, Chandra Sekhar Biswas, Yuhang Wu, Amin Ghavaminejad, Florian J. Stadler. Small and large amplitude oscillatory shear behavior of supramolecular gels based on dopamine-boronic acid interactions.Journal of Rheology. 2019, 63 (3), 391-404.

10. Lei Du, Amin Ghavaminejad, Zhi-chao Yan, Chandra Sekhar Biswas, Florian J. Stadler. Effect of a functional polymer on the rheology and microstructure of sodium alginate. Carbohydrate Polymers, 2018, 199: 58-67.

11. Lei Du, Amin Ghavaminejad, Mohammad Vatankhah-varnoosfaderani, Florian. J. Stadler. Study of the interactions of zwitterions and carbon nanotubes by nonlinear rheology in aqueous environment. Langmuir,2019, 35:1964-1972.

12. Lei Du, Tom Brenner, Jingli Xie, Shingo Matsukawa. A study on phase separation behavior in kappa/iota carrageenan mixtures by micro DSC, rheological measurements and simulating water and cations migration between phases. Food Hydrocolloids, 2016, 55: 81-88.

发明专利：

[1] 谢静莉，方明，李鹏，吴艳玲，杜磊，魏东芝. 降血压多肽，ZL 2013101240332.

联系方式：

办公室：实验18楼707；

电话：021-64251803

通讯地址：上海市徐汇区梅陇路130号华东理工大学，200237

邮箱：dulei@ecust.edu.cn